Timoptic 0.5% Ophthalmic Solution
Timoptic 0.5% is a long-established timolol formulation valued in veterinary ophthalmology for its consistent intraocular pressure lowering and wide clinical availability; its status as a legacy brand gives clinicians confidence and a mature pharmacovigilance record compared with newer entrants. Financially it often benefits from broad distribution and stable pricing versus proprietary selective agents like Betoptic S, making it a practical first-line topical beta blocker for many canine glaucoma cases when nonselective therapy is acceptable.
Proven IOP control
Clear watery drop
Proven IOP control
Clear watery drop
Review Summary
"Veterinarians and dog owners report Timoptic 0.5% reliably lowers intraocular pressure with regular use and is valued for affordability; some dogs experience transient ocular sting or occasional systemic effects like mild lethargy. Overall users find it effective but note monitoring is required for side effects."
Easy once-daily tailwag
Non‑selective timolol that effectively lowers intraocular pressure in canine glaucoma.
Easy once-daily tailwag
Non‑selective timolol that effectively lowers intraocular pressure in canine glaucoma.
Increased Safety & Security
Time-Saving Convenience
Timoptic 0.5% is a long-established timolol formulation valued in veterinary ophthalmology for its consistent intraocular pressure lowering and wide clinical availability; its status as a legacy brand gives clinicians confidence and a mature pharmacovigilance record compared with newer entrants. Financially it often benefits from broad distribution and stable pricing versus proprietary selective agents like Betoptic S, making it a practical first-line topical beta blocker for many canine glaucoma cases when nonselective therapy is acceptable.
Proven IOP control
Clear watery drop
Easy once-daily tailwag
Non‑selective timolol that effectively lowers intraocular pressure in canine glaucoma.
Widely available as a branded/generic product, making it cost‑effective for chronic use.
Proven IOP control
Clear watery drop
Easy once-daily tailwag
Non‑selective timolol that effectively lowers intraocular pressure in canine glaucoma.
Widely available as a branded/generic product, making it cost‑effective for chronic use.
$25-70 USD
Trusopt (Dorzolamide) 2% Ophthalmic Solution
Trusopt is the reference-brand dorzolamide 2% aqueous solution with a long clinical track record and predictable topical carbonic anhydrase inhibition that veterinarians rely on for dogs. Its sterile solution formulation is easy to instill and generally causes less transient visual disturbance than suspensions, making it a practical and cost-effective branded choice compared with combination products and some suspension-based alternatives.
Rapid IOP drop
Low irritation
Rapid IOP drop
Low irritation
Review Summary
"Most long‑term users report reliable intraocular pressure reduction in dogs, though many note a transient stinging/burning on application; overall effective but often pricier than generics."
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Increased Safety & Security
Time-Saving Convenience
Trusopt is the reference-brand dorzolamide 2% aqueous solution with a long clinical track record and predictable topical carbonic anhydrase inhibition that veterinarians rely on for dogs. Its sterile solution formulation is easy to instill and generally causes less transient visual disturbance than suspensions, making it a practical and cost-effective branded choice compared with combination products and some suspension-based alternatives.
Rapid IOP drop
Low irritation
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Brand formulation with consistent drop size and preservative profile; often used off-label in dogs for glaucoma.
Rapid IOP drop
Low irritation
Clinic staple, woof!
Dorzolamide 2% topical solution that lowers intraocular pressure by inhibiting carbonic anhydrase.
Brand formulation with consistent drop size and preservative profile; often used off-label in dogs for glaucoma.
$35-80 USD
Diamox 250mg Tablets
Diamox 250mg is presented as the market-leading acetazolamide formulation for systemic carbonic anhydrase inhibition in canine glaucoma because of longstanding clinical use and wide availability; veterinarians favor it for predictable efficacy and an established pharmacokinetic profile. While typically costlier than generic acetazolamide options, its recognized brand quality and robust supply chain make it a go-to for practices that prioritize consistency over price when managing chronic intraocular pressure in dogs.
Lowers eye pressure
Oral tablet convenience
Lowers eye pressure
Oral tablet convenience
Review Summary
"Dog owners and vets report Diamox 250mg is effective at lowering intraocular pressure and works reliably when dosed correctly, though many note pronounced diuresis and occasional lethargy or appetite changes as common side effects."
Veterinary favorite — classic
Brand-name acetazolamide (Diamox) commonly used systemically to reduce intraocular pressure in dogs by inhibiting carbonic anhydrase.
Veterinary favorite — classic
Brand-name acetazolamide (Diamox) commonly used systemically to reduce intraocular pressure in dogs by inhibiting carbonic anhydrase.
Increased Safety & Security
Time-Saving Convenience
Diamox 250mg is presented as the market-leading acetazolamide formulation for systemic carbonic anhydrase inhibition in canine glaucoma because of longstanding clinical use and wide availability; veterinarians favor it for predictable efficacy and an established pharmacokinetic profile. While typically costlier than generic acetazolamide options, its recognized brand quality and robust supply chain make it a go-to for practices that prioritize consistency over price when managing chronic intraocular pressure in dogs.
Lowers eye pressure
Oral tablet convenience
Veterinary favorite — classic
Brand-name acetazolamide (Diamox) commonly used systemically to reduce intraocular pressure in dogs by inhibiting carbonic anhydrase.
Dosing is weight-based and typically requires veterinary oversight with periodic blood work for electrolytes and renal function.
Lowers eye pressure
Oral tablet convenience
Veterinary favorite — classic
Brand-name acetazolamide (Diamox) commonly used systemically to reduce intraocular pressure in dogs by inhibiting carbonic anhydrase.
Dosing is weight-based and typically requires veterinary oversight with periodic blood work for electrolytes and renal function.
$150-250 USD
Xalatan (latanoprost) 0.005% ophthalmic solution
Xalatan (latanoprost) is widely regarded as a first-line topical prostaglandin analogue for acute intraocular pressure (IOP) lowering in dogs because of its rapid onset and strong IOP-reducing effect; its long history and availability as a generic translate into lower cost per dose compared with some newer branded alternatives. Compared with travoprost and bimatoprost, latanoprost often produces faster pressure drops, while it lacks the preservative-free delivery advantage of tafluprost (Zioptan) and the tolerability profile of lower-potency agents like unoprostone (Rescula).
Rapid IOP drop (zippy)
Proven track record (veteran)
Rapid IOP drop (zippy)
Proven track record (veteran)
Review Summary
"Veterinarians and dog owners report rapid, reliable intraocular pressure reduction with latanoprost in dogs, though many note transient ocular irritation, miosis and gradual periocular/pigment changes with long‑term use."
Easy once-daily (one-and-done)
Latanoprost 0.005% provides reliable once‑daily IOP reduction and is widely used off‑label in dogs.
Easy once-daily (one-and-done)
Latanoprost 0.005% provides reliable once‑daily IOP reduction and is widely used off‑label in dogs.
Increased Safety & Security
Time-Saving Convenience
Xalatan (latanoprost) is widely regarded as a first-line topical prostaglandin analogue for acute intraocular pressure (IOP) lowering in dogs because of its rapid onset and strong IOP-reducing effect; its long history and availability as a generic translate into lower cost per dose compared with some newer branded alternatives. Compared with travoprost and bimatoprost, latanoprost often produces faster pressure drops, while it lacks the preservative-free delivery advantage of tafluprost (Zioptan) and the tolerability profile of lower-potency agents like unoprostone (Rescula).
Rapid IOP drop (zippy)
Proven track record (veteran)
Easy once-daily (one-and-done)
Latanoprost 0.005% provides reliable once‑daily IOP reduction and is widely used off‑label in dogs.
Available as brand (Xalatan) and cheaper generics, increasing accessibility for long‑term treatment.
Rapid IOP drop (zippy)
Proven track record (veteran)
Easy once-daily (one-and-done)
Latanoprost 0.005% provides reliable once‑daily IOP reduction and is widely used off‑label in dogs.
Available as brand (Xalatan) and cheaper generics, increasing accessibility for long‑term treatment.
$60-120 USD
Alphagan P 0.15% Ophthalmic Solution
Alphagan P 0.15% is positioned as a potent topical alpha-2 adrenergic agonist for canine glaucoma, offering a higher brimonidine concentration together with a Purite preservative designed to limit ocular surface toxicity. For the specific use case of topical antiglaucoma therapy in dogs it is often preferred for acute or refractory intraocular pressure elevation compared with the 0.1% formulation because of stronger IOP reduction, and though it typically carries a premium versus generic brimonidine it delivers a consistent proprietary formulation that can reduce the need for adjunctive agents.
Stronger pressure drop
Purite-preserved sparkle
Stronger pressure drop
Purite-preserved sparkle
Review Summary
"Long-term users report Alphagan P 0.15% frequently reduces intraocular pressure in dogs and is generally well tolerated, though some pets experience mild ocular irritation or transient lethargy. Many owners and vets consider it effective as part of chronic glaucoma management when monitored."
Rapidly soothing touch
Contains brimonidine 0.15%, an alpha-2 agonist used to reduce intraocular pressure in humans and commonly used off-label in dogs under veterinary guidance.
Rapidly soothing touch
Contains brimonidine 0.15%, an alpha-2 agonist used to reduce intraocular pressure in humans and commonly used off-label in dogs under veterinary guidance.
Increased Safety & Security
Time-Saving Convenience
Alphagan P 0.15% is positioned as a potent topical alpha-2 adrenergic agonist for canine glaucoma, offering a higher brimonidine concentration together with a Purite preservative designed to limit ocular surface toxicity. For the specific use case of topical antiglaucoma therapy in dogs it is often preferred for acute or refractory intraocular pressure elevation compared with the 0.1% formulation because of stronger IOP reduction, and though it typically carries a premium versus generic brimonidine it delivers a consistent proprietary formulation that can reduce the need for adjunctive agents.
Stronger pressure drop
Purite-preserved sparkle
Rapidly soothing touch
Contains brimonidine 0.15%, an alpha-2 agonist used to reduce intraocular pressure in humans and commonly used off-label in dogs under veterinary guidance.
Formulated with Purite preservative to minimize ocular surface irritation compared with older preservatives.
Stronger pressure drop
Purite-preserved sparkle
Rapidly soothing touch
Contains brimonidine 0.15%, an alpha-2 agonist used to reduce intraocular pressure in humans and commonly used off-label in dogs under veterinary guidance.
Formulated with Purite preservative to minimize ocular surface irritation compared with older preservatives.
$60-100 USD
Xalacom (latanoprost-timolol)
Xalacom couples latanoprost with timolol to offer a potent prostaglandin‑based combination that is widely available and often available in lower‑cost generic forms, giving it a strong cost‑competitiveness for long‑term management in dogs. Technically similar in on‑target efficacy to other prostaglandin combinations such as DuoTrav, Xalacom's main market advantage is broader availability and affordable pricing, making it a practical choice when budget and access are decisive factors.
Fast-acting prostaglandin
Sharp IOP reduction
Fast-acting prostaglandin
Sharp IOP reduction
Review Summary
"Xalacom is widely regarded as effective and fast‑acting for glaucoma control, with many users reporting consistent IOP reduction; some note periocular pigmentation or eyelash changes and occasional ocular discomfort. Overall reviews are positive when used under veterinary guidance."
Bedtime-friendly dose
Contains latanoprost (potent prostaglandin analogue) combined with timolol for complementary IOP lowering
Bedtime-friendly dose
Contains latanoprost (potent prostaglandin analogue) combined with timolol for complementary IOP lowering
Increased Safety & Security
Time-Saving Convenience
Xalacom couples latanoprost with timolol to offer a potent prostaglandin‑based combination that is widely available and often available in lower‑cost generic forms, giving it a strong cost‑competitiveness for long‑term management in dogs. Technically similar in on‑target efficacy to other prostaglandin combinations such as DuoTrav, Xalacom's main market advantage is broader availability and affordable pricing, making it a practical choice when budget and access are decisive factors.
Fast-acting prostaglandin
Sharp IOP reduction
Bedtime-friendly dose
Contains latanoprost (potent prostaglandin analogue) combined with timolol for complementary IOP lowering
Latanoprost’s once‑daily prostaglandin effect plus timolol’s aqueous suppression offers strong pressure control
Fast-acting prostaglandin
Sharp IOP reduction
Bedtime-friendly dose
Contains latanoprost (potent prostaglandin analogue) combined with timolol for complementary IOP lowering
Latanoprost’s once‑daily prostaglandin effect plus timolol’s aqueous suppression offers strong pressure control
$90-180 USD