Top 7 Equine Regenerative Therapies and Biologic Products in the United States (2025): Veterinary-Approved PRP, Stem Cell, ACS and Biologic Scaffold Options - Which 7 Leading Solutions American Vets Trust?

Arthrex ACP Double Syringe System is positioned as a best-in-class option for equine first aid because its simple closed double-syringe design enables rapid bedside preparation of platelet-rich plasma with minimal equipment, which keeps per-treatment costs low and logistics straightforward in field settings. Compared with filtration or tube-based competitors on this list, it trades some of the highest-yield laboratory performance for speed, ease of use and broader distribution — making it a practical, cost-effective choice for routine on-site wound and tendon management.

A ready-to-use, performance-focused media and accessory kit optimized for rapid MSC proliferation and streamlined scale-up workflows, offering predictable expansion that can reduce time-to-dose in equine first-aid applications. Financially attractive for clinics that prioritize fast expansion and lower per-cell production cost, it competes directly with defined kits like MesenCult-ACF by trading some regulatory-oriented formulation features for speed and cost-efficiency, and pairs well with both static and bioreactor expansion systems on this list.

Arthrex ACP is ranked as a market leader for user-friendly, point-of-care autologous conditioned plasma that delivers a consistent platelet concentrate with minimal equipment and short processing time, ideal for equine first-aid interventions in busy clinic or ambulatory settings. Compared with more complex cytokine-driven systems like IRAP II, ACP’s chief advantages are lower upfront cost, rapid turnaround, and simplified staff training, offering a financially attractive option for routine acute treatments despite a more modest anti‑inflammatory cytokine profile. Its commercial strength lies in scalability and predictable, low-complexity workflows for clinics prioritizing throughput and cost control.

MIMEDX EpiFix Equine represents the market-leading dHACM (dehydrated human amnion/chorion membrane) approach, prized for rich native growth factors and anti-inflammatory signals that can accelerate healing in complex or chronic equine wounds. Technically it often delivers faster biologic modulation than pure SIS or UBM scaffolds and may reduce overall treatment time, but it commands a premium price; it is typically chosen when clinical outcome acceleration outweighs per-unit cost compared with more economical ECM scaffolds such as VetBioSIS or Vetrix BioSIS.

Pro-Stride APS earns a top position for equine first-aid use because its APS (autologous protein solution) formulation emphasizes concentrated anti-inflammatory cytokines and growth factors in a single, point-of-care kit that speeds on-farm treatment. Compared with centrifuge-dependent PRP kits in this list, Pro-Stride targets a higher ratio of anti-catabolic mediators which can reduce follow-up interventions and overall cost per case for acute joint or soft-tissue flare-ups. Its technical advantage is a streamlined, clinic-friendly workflow that balances potency with affordability for routine stable-side care.

VetBiotek ExoEquine is positioned as the best-in-class formulation for equine first-aid due to its high-purity GMP-grade exosome concentrate and a stabilised, ready-to-use delivery that enables rapid on-field application. Its technical edge — higher particle concentration and extended shelf stability — gives it a per-dose cost advantage versus premium clinical offerings like RegenEQ while outperforming secretome-only options such as EquiCell in acute regenerative potency. Compared with ProVet and CanEquine, ExoEquine emphasizes scalability and laboratory-grade quality, making it a go-to for clinics prioritising consistent, reproducible outcomes.