Zoetis Tetanus Toxoid is a focused, monovalent vaccine favored for targeted tetanus prevention in horses; its simplicity makes it cost-effective for clinics and owners who only need tetanus protection rather than broad-spectrum coverage. Compared with the multivalent products in this list, it typically offers lower per-dose cost and a straightforward administration profile, making it the practical choice when tetanus is the sole concern.
Rapid immune lift
Simple dosing routine
Rapid immune lift
Simple dosing routine
Review Summary
"Widely praised for reliable tetanus protection and consistent results; users report few side effects and straightforward handling, though some note it’s pricier than generic alternatives."
Vet-favorite wink
Inactivated tetanus toxoid formulated specifically to induce active immunity in horses.
Vet-favorite wink
Inactivated tetanus toxoid formulated specifically to induce active immunity in horses.
Enhanced Physical Well-Being
Time-Saving Convenience
Zoetis Tetanus Toxoid is a focused, monovalent vaccine favored for targeted tetanus prevention in horses; its simplicity makes it cost-effective for clinics and owners who only need tetanus protection rather than broad-spectrum coverage. Compared with the multivalent products in this list, it typically offers lower per-dose cost and a straightforward administration profile, making it the practical choice when tetanus is the sole concern.
Rapid immune lift
Simple dosing routine
Vet-favorite wink
Inactivated tetanus toxoid formulated specifically to induce active immunity in horses.
Typically supplied as a multi-dose vial for use in a primary series and routine boosters per label.
Rapid immune lift
Simple dosing routine
Vet-favorite wink
Inactivated tetanus toxoid formulated specifically to induce active immunity in horses.
Typically supplied as a multi-dose vial for use in a primary series and routine boosters per label.
$40-80 USD
Nobivac Rabies is a widely used leader for equine rabies control due to its manufacturer’s global supply chain and consistent batch-to-batch quality, delivering predictable immunogenicity and broad regulatory acceptance. Typically priced at a premium similar to Imrab 3, Nobivac’s strength is reduced logistical risk and dependable availability—features valued by veterinarians and owners managing high-value or internationally traveling horses.
Consistent efficacy
Low side-effects
Consistent efficacy
Low side-effects
Review Summary
"Nobivac Rabies is a market-leading choice noted for consistent potency, reliable safety, and strong veterinarian trust; most users report few adverse events."
Cold-chain hardy
Produced by a major manufacturer with broad distribution to veterinary clinics
Cold-chain hardy
Produced by a major manufacturer with broad distribution to veterinary clinics
Enhanced Physical Well-Being
Time-Saving Convenience
Nobivac Rabies is a widely used leader for equine rabies control due to its manufacturer’s global supply chain and consistent batch-to-batch quality, delivering predictable immunogenicity and broad regulatory acceptance. Typically priced at a premium similar to Imrab 3, Nobivac’s strength is reduced logistical risk and dependable availability—features valued by veterinarians and owners managing high-value or internationally traveling horses.
Consistent efficacy
Low side-effects
Cold-chain hardy
Produced by a major manufacturer with broad distribution to veterinary clinics
Inactivated rabies vaccine commonly used in routine equine rabies control programs
Consistent efficacy
Low side-effects
Cold-chain hardy
Produced by a major manufacturer with broad distribution to veterinary clinics
Inactivated rabies vaccine commonly used in routine equine rabies control programs
$150-230 USD
West Nile-Innovator is positioned as a market-leading, widely adopted West Nile vaccine for horses due to a long track record of field use and broad veterinary distribution, making it a default choice for large stables and boarding operations. Compared with the other listed vaccines it emphasizes proven real-world efficacy and supply-chain availability, which can translate into lower acquisition risk and predictable budgeting for equine operations that prioritize established performance over newest-technology premiums.
Fast immune kick
Season-long shield
Fast immune kick
Season-long shield
Review Summary
"Most long-term users report reliable protection with few adverse reactions and easy handling; occasional local soreness is the most common complaint. Overall seen as a dependable, broadly used West Nile vaccine for horses."
Mosquito's nightmare
Inactivated whole-virus vaccine with a long track record of field use and well-understood safety profile.
Mosquito's nightmare
Inactivated whole-virus vaccine with a long track record of field use and well-understood safety profile.
Enhanced Physical Well-Being
Recreational Enjoyment
West Nile-Innovator is positioned as a market-leading, widely adopted West Nile vaccine for horses due to a long track record of field use and broad veterinary distribution, making it a default choice for large stables and boarding operations. Compared with the other listed vaccines it emphasizes proven real-world efficacy and supply-chain availability, which can translate into lower acquisition risk and predictable budgeting for equine operations that prioritize established performance over newest-technology premiums.
Fast immune kick
Season-long shield
Mosquito's nightmare
Inactivated whole-virus vaccine with a long track record of field use and well-understood safety profile.
Typically given as a two-dose initial series followed by annual boosters for ongoing protection.
Fast immune kick
Season-long shield
Mosquito's nightmare
Inactivated whole-virus vaccine with a long track record of field use and well-understood safety profile.
Typically given as a two-dose initial series followed by annual boosters for ongoing protection.
$70-140 USD
Vetera EWT+WNV is positioned as a cost-efficient, multivalent option for equine encephalomyelitis vaccination, combining Eastern/Western/Tetanic coverage with West Nile protection to reduce the number of clinic visits. It stands out against single-focus or higher-priced multivalents on this list by offering broad coverage in a single dose, which translates to lower per-horse administration cost and streamlined herd vaccination logistics compared with some premium competitors.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Review Summary
"Users report strong, reliable protection from EWT and West Nile with generally mild, short-lived injection-site reactions; many horse owners and vets consider it a dependable annual combo vaccine."
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Enhanced Physical Well-Being
Time-Saving Convenience
Recreational Enjoyment
Vetera EWT+WNV is positioned as a cost-efficient, multivalent option for equine encephalomyelitis vaccination, combining Eastern/Western/Tetanic coverage with West Nile protection to reduce the number of clinic visits. It stands out against single-focus or higher-priced multivalents on this list by offering broad coverage in a single dose, which translates to lower per-horse administration cost and streamlined herd vaccination logistics compared with some premium competitors.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Inactivated (killed) vaccine typically given as a two-dose primary series with annual boosters thereafter.
EWT + WNV combo — one-shot hero
Convenient combo — fewer vet runs
Proven field use — barn-approved
Combines protection against Eastern and Western equine encephalomyelitis, tetanus and West Nile in a single formulation.
Inactivated (killed) vaccine typically given as a two-dose primary series with annual boosters thereafter.
$35-70 USD per dose
Vetera Gold XP is positioned as best-in-class for multivalent vaccine formulations for horses thanks to a proprietary adjuvant system and broad antigenic coverage that promotes longer-lasting immunity and reduced annual booster needs. Compared with Prestige V + WNV and Fluvac Innovator 6 it trades a modestly higher per-dose cost for fewer re-vaccinations per year, and it delivers a wider antigen mix than EquiVac Innovator 4-Way or the more core-focused Core EQ Innovator, giving strong technical and lifetime-cost advantages for high-value equine athletes.
Broad protection
Long-lasting immunity
Broad protection
Long-lasting immunity
Review Summary
"Users report Vetera Gold XP provides consistent, broad protection with few adverse reactions and is valued for its long-lasting immunity; many veterinarians cite reliable performance in herd vaccination programs."
Barn-approved single-dose
Multivalent formulation that combines tetanus with Eastern/Western encephalomyelitis and West Nile components.
Barn-approved single-dose
Multivalent formulation that combines tetanus with Eastern/Western encephalomyelitis and West Nile components.
Enhanced Physical Well-Being
Time-Saving Convenience
Vetera Gold XP is positioned as best-in-class for multivalent vaccine formulations for horses thanks to a proprietary adjuvant system and broad antigenic coverage that promotes longer-lasting immunity and reduced annual booster needs. Compared with Prestige V + WNV and Fluvac Innovator 6 it trades a modestly higher per-dose cost for fewer re-vaccinations per year, and it delivers a wider antigen mix than EquiVac Innovator 4-Way or the more core-focused Core EQ Innovator, giving strong technical and lifetime-cost advantages for high-value equine athletes.
Broad protection
Long-lasting immunity
Barn-approved single-dose
Multivalent formulation that combines tetanus with Eastern/Western encephalomyelitis and West Nile components.
Typically administered as a primary two‑dose series with regular boosters for ongoing immunity.
Broad protection
Long-lasting immunity
Barn-approved single-dose
Multivalent formulation that combines tetanus with Eastern/Western encephalomyelitis and West Nile components.
Typically administered as a primary two‑dose series with regular boosters for ongoing immunity.
$180-300 USD